A member asked:

I take 4 mg of folic acid per day with 10 mg methotrexate weekly. is this too much folic acid?

A doctor has provided 1 answer
Dr. Julie Abbott answered

Specializes in Preventive Medicine

Probably too much: Methotrexate seems to deplete the body of folic acid, and, while controversial, most rheumatologists recommend supplementation. The most common dose is 1 mg per day, but doses range from 5 - 10 mg weekly. 4 mg/day seems higher than usually recommended. There is some concern that too much folic acid might reduce the effectiveness of Methotrexate. Needs review with your doctor. Good wishes!

Answered 8/25/2017

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