Generally, how potent is clonidine when compared to other hypertensive medications, such as beta blockers and ace inhibitors? or, is it so individual?

Hypertension: Current 1st line medication for hypertension or high blood pressure is a thiazide diuretic (water pill) like hctz (hydrochlorothiazide) unless you have a compelling reason eg diabetes, heart disease, kidney disease, etc for something else. Clonidine is far down list. It works but all BP meds work. Down side of Clonidine is rebound hypertension if you forget to take dose. Some find it sedating. Potency depends upon dose.