Can someone still be treated for aspirin od 48hrs after ingestion or is it too late then? taking into account dehydration and low kidney function?

Sure: Some problems form overdose may come later in the course, so definitely get treated. I recommend calling the poison control number toll free and you can speak to an expert, ... 1-800-222-1222. Best wishes.

May need support: Generally, the acute management of an Aspirin od would be over by them, but severe cases with respiratory depression, persistent metabolic disturbances and mental status changes would still need treatment and support. This coud include intubation, IV fluids and even dialysis.

Aspirin toxicity: Serious Aspirin overdose that is life-threatening usually kills within the first 48 hours. It is highly unlikely the patient would be alive and stable at 48 hours. Elevated Aspirin levels can be seen at 48 hours but would more likely be associated with chronic Aspirin toxicity which is treated by stopping the aspirin. The level is graphed by time from ingestion on an Aspirin toxicity chart.