A member asked:

Can anyone tell me about a new glaucoma treatment called rock inhibitors for glaucoma?

5 doctors weighed in across 3 answers

New medication class: Rock inhibitors ( rho-kinase inhibitors) are not fda approved yet but unique in their approach to specifically target cells in the trabecular mesh work (drain of eye) to improve aqueous outflow. They may also manifest neuroprotection, anti inflammatory, and enhancement of optic nerve blood flow effects. Stay tuned to this most fascinating class of medications.

Answered 12/10/2013

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Rho kinase: Its a new drug still under development. Rho kinase (rock) inhibitors target cells in the trabecular meshwork to enhance aqueous humor outflow, this in turn decreases intraocular pressure, which is the goal for glaucoma treatment.

Answered 7/1/2014

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Dr. Richard Lehrer answered

Specializes in Glaucoma

New Class of Drug: Rock inhibitors or rho-kinase inhibitors are currently under investigation for glaucoma therapy by at least 2 pharma companies. They show promise in animal models and early phase clinical trials. They may have some unwanted side effects and probably will not be on the market for several years if they are approved by the fda.

Answered 2/8/2015

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