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A member asked:

For what length of time can methotrexate make you sick?

A doctor has provided 1 answer

See details: What do you mean by sick? If you mean GI problems such as nausea and vomiting, it may last a few days. I would suggest that the Methotrexate be given by injection subcutaneously instead of by mouth. It is easy to do and will avoid GI issues. It may also be more effective this way.

Answered 7/19/2019

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