ANA is 95% sensitive: That means that about 5% of patients with lupus will be negative or ana. There are a few other tests to perform in ANA negative pts. In whom there is still high index of suspicion. Ss-a, ss-b can be sometimes found in ANA negative patients. The rash could be biopsied and there may be typical pathological findings consistent with lupus.
Answered 6/12/2014
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Depends on symptoms: Keep in mind that although lupus is a mysterious disease, there are specific symptoms or signs necessary to make a diagnosis. These include particular rashes, fluid on the heart or lungs, kidney problems, joint inflammation (not only pain), mouth ulcers seen by your doctor, low blood counts, hair loss, or neurological problems. If none are present, it is not likely to be lupus even with +ana.
Answered 9/15/2015
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