Variable: Cheapest is probably an over-the-counter cleanser or topical that contains benzoyl peroxide, salicylic acid or zinc. The prescription products are usually more effective because they are stronger and have more of the active ingredient, as well as contain antibiotics. Differin and retin a (tretinoin) are prescriptions. There is no "best" because everyone's skin reacts differently to different products.
Answered 11/28/2017
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