Can people who lose weight with diet pills look different than people who lose weight naturally?

Tough question: Since most diet pills don't actually work, at least in the long term, the glib answer is that those who use them look different by being heavier. In general, the impact of weight loss on looks depends on how one does it. Calorie restriction alone can cause loss of both muscle and fat; adding exercise can sustain and even add muscle while reducing fat, which leads to a better look, overall.

Losing weight: Those who work out and eat nutritiously - may have more muscle tone than those who just take diet pills.