A 43-year-old member asked:
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how much vitamin b12 should i take if i take daily colchicine for fmf?

2 doctor answers
Dr. Ronald Krauser
51 years experience Rheumatology
None: You do not need to take any supplemental vitamin B12 if you are on colchicine.
Answered on Jun 24, 2014
Dr. Tracy Lovell
20 years experience Rheumatology
See your doctor: Colchicine or Colcrys can decrease the absorption of B12 on occasion which can lead to neuropathy and anemia. Have your doctor check your B12 level in order to determine how much you need. However; B12 is a water soluble vitamin---what you do not need will pass in the urine.
Answered on Jun 24, 2014

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500mcg: I recommend 500mcg, but taking sl B12 2500mcg will also lower a factor in heart disease, called homocysteine.
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