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A member asked:
I know that the typical test for sickle-cell anemia is a hemoglobin electrophoresis, but will you be able to see the sickle shape of the blood cells?
3 doctors weighed in across 2 answers
No: A hemoglobin electrophoresis is not a look at the blood cells, rather it is a determination of the type(s) of hemoglobin in the red blood cells. Cells are looked at under the microscope when a blood count is performed. Sickled cells can then be seen.
Answered 9/21/2020
5.2k views
Yes: Sick led cells are readily seen on a peripheral blood smear. It's worth knowing that the irreversibly sick led cells that you see on a smear are not necessarily the ones that cause the problem. In order for a cell at risk for sickling to occlude the small blood vessels (capillaries), they first must be able to enter them. In other words they must be deformable. They become occlusive in the vessel.
Answered 7/4/2015
5k views
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