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A member asked:
I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. c3 of 113, c4 of 53. a rash on face could it be lupus?
2 doctors weighed in across 2 answers
Yes: Lupus is a major consideration. The microsomal antibodies suddest that autoimmune thyroid disease is also present. See a rheumatologist if you have done so already.
Answered 3/15/2021
4.5k views
Yes: If the rash fits the butterfly or discoid rash or the subacute lupus skin lesion. ANA titer is usually high in lupus; you have not listed yours. The C3 and C4 are markers of disease activity and famously nonspecific. Don't try to self-diagnose; your age of 54 is a bit high for new-onset lupus though it's not impossible.
Answered 9/13/2015
4.5k views
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Does c3 & c4 have to be low to indicate lupus. My c3 was the only one low. I also had positive ana & I had more blood work done, but not back yet.
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