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A member asked:
What different types of sickle cell exist?
A doctor has provided 1 answer
SS, SC, Sb-thal: The letters refer to the form of the beta globin gene (a is normal, s is sickle cell, c is another form of beta globin). Ss is severe homozygous sickle cell anemia. Sc. Is moderately severe form. S-beta-thalassemia is variable disease where one beta globin is sickle and the other has a different mutation that reduces the amount of normal a made. Beta zero makes no a; it results in severe disease.
Answered 1/10/2015
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