What type of disorder is a sickle cell and what part of the body does it affect?

Sickled blood cells: Sickle cell anemia is a disorder of the red material, hemoglobin, inside red blood cells. The hemoglobin clumps up when stressed changing the shape of the blood cells so that they can stop blood flow through small blood vessels. Since blood flows through the whole body, clumped sicke cells can cause hypoxic damage to any tissue. Read more: www.Nhlbi.Nih.Gov/health/health-topics/topics/sca/.

You can't prevent it: Sickle cell dz is a constitutional disease caused by a mutation in codon 6 of the beta globin gene that changes glutamate to valine in the encoded protein. This protein contributes 2 subunits to hemoglobin, the oxygen carrier in rbcs. Sickling behavior can block blood flow to any tissue via the smallest blood vessels so can affect virtually any tissue. Ask if you wish more specific info.