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A member asked:
I have small fiber neuropathy diagnosed by skin biopsy. my kappa free light chain was slightly elevated with normal lambda and normal kappa/lambda ratio. is it possible i have amyloidosis?
A doctor has provided 1 answer
NO, there is no proof of amyloidosis so far, and there seems to be no amyloid deposition noted on the biopsy. The kappa/ lambda data is also non-diagnostic. The most frequent cause of isolated small fiber neuropathy in the USA is pre-diabetes and diabetes. There are several other causes. Has your physician discussed possible next steps? Do you need a second opinion?
Answered 7/19/2023
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