A member asked:

Does regular isosorbide mononitrate longer lasting than isosorbide dinitrate ? doctor prescribed isosorbide mononitrate 10 mg tab once daily and said its longer than twice daily isosorbide dinitrate ? is that true. ?

Q: does regular isosorbide mononitrate longer lasting than isosorbide dinitrate ? doctor prescribed isosorbide mononitrate 10 mg tab once daily and said its longer than twice daily isosorbide dinitrate ? is that true. ?

: Yes, regular isosorbide mononitrate lasts longer than isosorbide dinitrate but with one a day dose you have to use extended release formula. Use REGULAR isosorbide mononitrate for vasospasm prevention then you have to use twice a day, 7 hours apart (instead of 12 hours apart) for minimizing tolerance. Good luck.

A doctor has provided 1 answer

Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

Yes, regular isosorbide mononitrate lasts longer than isosorbide dinitrate but with one a day dose you have to use extended release formula. Use REGULAR isosorbide mononitrate for vasospasm prevention then you have to use twice a day, 7 hours apart (instead of 12 hours apart) for minimizing tolerance. Good luck.

Answered 6/4/2023

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A member asked:

Does regular isosorbide mononitrate longer lasting than isosorbide dinitrate ? doctor prescribed isosorbide mononitrate 10 mg tab once daily and said its longer than twice daily isosorbide dinitrate ? is that true. ?

A doctor has provided 1 answer

Dr. Hiep Le answered

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