A member asked:

Was prescribed mestinon for pots. are there adverse effects if taking long term? i read that it can cause problems with response to acth. yes, will ask with my doctor but would appreciate more doctors inputs. can it cause more problems longterm?

A doctor has provided 1 answer
Dr. Samuel Galima answered

Specializes in Family Medicine

Pyridostigmine (Mestinon) is a Acetylcholinesterase (AChE) Inhibitor. It's mechanism of action is to stop the destruction of acetylcholine by AChE, which increases acetylcholine and its transmission of impulses at the neuromuscular junction. ACTH is an abbreviation for Adrenocorticotropic hormone, not AChE. Mestinon is FDA approved to treat Myasthenia Gravis and used as a reversal agent

Answered 4/8/2023

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