A member asked:

A few hours post trans ischemic stroke of 87 yr old - right side mobility was in order as well as speech (bit slow and slurry but clear). 24+ hours later, speech massively impacted: unclear, slurry and drifting. what could this regression be due to?

3 doctors weighed in across 2 answers

It is not regression but manifestation of full damage of stroke and needs immediate attention

Answered 2/26/2023

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Following the initial stroke event, brain tissue distal to the obstruction gets inflamed, swollen, and may be irreversibly damaged. This localized cerebral oedema maximizes at 24-36 hrs. You describe the expected outcome in the garden variety stroke.

Answered 3/6/2023

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