A member asked:

For hiv test is p24 ag present in hiv 2 ? some websites say p24 is present in hiv2 and some websites say it is not. i did hiv 1/2 abs / p24 ag after 182 days and the result is negative. i am afraid of the seroconversion delay?

A doctor has provided 1 answer
Dr. Hunter Handsfield answered

Specializes in Infectious Disease

"Seroconversion delay" is an urban myth; it never happens. HIV2 has p24 antigen, but different than the p24 in HIV1 and not detected in the HIV AgAb (4th generation) blood tests. Therefore, those tests are conclusive for HIV2 after 8 weeks, vs. 4-6 weeks for HIV1. HIV2 is virtually absent in the US anyway, found mostly in people infected in Africa and their regular partners.

Answered 2/19/2023

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