A member asked:

At what stage of dementia diagnosis would a pet scan be performed to distinguish alzheimer's from frontal lobe dementia?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

The onset of frontal lobe dementia (FLD) is often 10 years or more earlier than Alzheimer's disease & significant personality changes & behavior problems are the hallmarks of FLD. However, in early stages of these disorders, the differential diagnosis may be difficult so I' d say FDG PET scan may be helpful in early stages if there's no significant difference in age of onset or manifestations.

Answered 2/13/2023

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There are subcategories of FTD and Alzheimer's which pre-dominantly present with speech difficulties. The clinical appearances may create some confusion, and here diagnostic precision may be enhanced via PET scanning.

Answered 2/13/2023

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