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What effect would you expect Angiotensin Receptor Blockers to have on the brain RAAS in people with Attention Deficit Disorder? Reduction in norepinephrine and sympathetic down regulation through AT1 blockade would reduce attention span and memory?
Do angiotensin receptor blockers cross the blood brain barrier? What effect do they have on the brain in people with anxiety or depression?
Have any of you doctors had a patient who complained about getting mental fog and anxiety from angiotensin receptor blockers (particularly Valsartan)? Do ARBs lower the level of norepinephrine in the brain? I read that they increase acetylcholine?
Do Angiotensin Receptor Blockers cause insomnia or sleep interruptions? I take Valsartan 40mg and I also have mild sleep apnea but I'm wondering whether the ARB is making my sleep worse because I wake up frequently and I get strange dreams?
Is the risk of hyperkalemia the same for all angiotensin receptor blockers? If I have normal kidney function prior to ARB usage, how likely am I to develop hyperkalemia?
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