A member asked:

I take lamotrigine for seizures. lately i havent been feeling well so we checked medication levels. im at 1.1 ug/ml. could that be why im getting breakthrough seizures, is that low?

2 doctors weighed in across 2 answers

Contact your neurologist ASAP, as your dosage is clearly sub-therapeutic and should be titrated upwards. Would anticipate far better control once this is addressed. In the meantime, do not drive, do activities at heights, use power equipment, bathe or swim alone.

Answered 9/11/2022

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Dr. Charles Turck answered

Specializes in Pharmacology

A level of 1.1 mcg/mL is lower than the target drug level in the blood and may well be the reason for breakthrough seizures. It’s going to be important that the doctor who’s following you for seizures is aware of that level if they are not already, but if they are not, notify them as soon as possible.

Answered 10/21/2022

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