A member asked:

Why is valsartan 80mg fda approved as only once a day dose for hypertension if the half life is only 6 hours? how does it last 24 hours?

A doctor has provided 1 answer
Dr. Theodore Davantzis answered

Specializes in Dentistry

Valsartan is an orally active, specific and selective ARB. After a single oral morning dose, the onset of its BP-lowering action is within 2 hours, with peak effect occurring within 4 to 6 hours. Morning once-a-day dosing ranging from 80 to 320 mg/d results in BP reduction throughout the entire 24 hours. ref: www.google.com

Answered 8/26/2022

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