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A member asked:
What is the most likely cause for high a/g ratio caused by progressively increasing albumin and decreasing globulin along with rbc/wbc drop over 2-month period in middle-aged female? symptoms incl. fatigue, body/muscle aches, joint pain, headaches?
2 doctors weighed in across 2 answers
We are usually faced with problem of high globulin levels seen in multple myeloma or systemic amyloidosis diagnosed by serum electrophoresis & immunofixation testing. However low globulin levels can be caused by liver,kidney,or intestinal pathology. Since you also have dropping wbc&rbc you may have an autoimmune disorder. Consult a rheumatologist. You may also be referred to a hematologist dependi
Answered 6/2/2022
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All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, it may have helped had you provided the actual results. Wish you good health!
Answered 6/2/2022
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