A member asked:

Elevated globulin slightly, is that normal? below are the my lab results. i am scared if its danger. total protein 7.8 g/dl albumin 3.8 g/dl globulin 4.0g/dl creatinine 0.69 mg/dl bun 11 mg/dl total bilirubin 0.5 mg/dl wbc - 4.7k/ul rbc -4.73k/ul?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

Your concern is correct. Yes, albumin/globulin ratio is usually 1.2 or higher but some people may have transient high globulin, e.g. post infection or post vaccination or some people may have permanent high globulin such as people with alcoholic liver disease. If this is a new finding and you do not belong to those groups, have it rechecked in 3 months. Lab error is more often than you thought.

Answered Nov 23, 2021

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Dr. Gurmukh Singh answered

Specializes in Pathology

Lab error is a very unlikely explanation. Elevated globulins can be due to polyclonal increase in immunoglobulins due to inflammation, and more seriously due to monoclonal immunoglobulins. Your doctor can order a protein electrophoresis examination to provide an idea of the underlying issue and direction for additional investigation.

Answered Nov 23, 2021

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