A member asked:

Can high dose cefelexin (1.5 g/day for a year) cause kidney problems or any other complications/side effects? my dr wants to start me on this for recurrent kidney infections but i just want to better understand the risks first?

2 doctors weighed in across 2 answers
Dr. Hunter Handsfield answered

Specializes in Infectious Disease

This is unusual treatment for recurrent or persistent urinary tract infection, but may be appropriate if your doctor has a good understanding of the nature of the infection and best treatment. It would be appropriate to see an infectious diseases specialist (or in UK, a genitourinary medicine [GUM] physician) if you haven't yet done so. Cephalexin has few side effects, kidney damage unlikely.

Answered 2/6/2022

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It is highly unusual to be on that dose for a year. Any medication taken for a long time can affect the kidneys but it depends on many other factors. You should be investigated thoroughly for cause of recurrent UTI by a Urologist before this course of action is taken. In the meantime drink water, empty your bladder frequently, keep the genital area clean and try some cranberry juice. Wish you well

Answered 2/6/2022

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