My little toe has a very thick nail, my middle toes nail sudden fell off and has grown back bumpy and yellow. no nail treatments work (have used each for several months) what can i do to clear up whatever is wrong?

You describe the possibility of have an infection to your nails. In the past it has been thought of a fungal infection but now recently been shown also bacteria with the fungus infect the nail. You can see your doctor and get a prescription for anti-fungal orally taken here in the United States I would say see a podiatrist. You can try topical antifungal and file the nail down but very difficult