My momma is tired and confused she is getting confused sometimes when she is talking?

Time to seek medical attention, many conditions can cause mental changes and work up is usually needed. Closest ER would be best unless her physician may be able to coordinate locally.

She should see a doctor for an examination ASAP. Good Luck

Depending upon age, degenerative cognitive issues may occur. A variety of causes can be considered, especially anticholinergic medication reactions and sleep disorders. Best to handle this ASAP. A local neurologist should be helpful.