A member asked:

Do psychiatric medications keep on blocking or acting on receptors after they are discontinued. are the same number of receptors freed up again ordead?

3 doctors weighed in across 2 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

Great question!: Our psychopharmacological researchers are asking similar questions. Once the meds are out of your body (some taking longer than others) your receptors should eventually re-establish their activity. However, some physiology has been altered, beyond levels of neurotransmitters. Re-equilibration may take time. Depending on the medication, there can be permanent changes, .

Answered 12/9/2013

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Dr. Jeffrey Satinover answered

Specializes in Psychiatry

Not exactly: Vulnerable genes only produce dire effects when the environment triggers them. Psych medications can indeed have a persistent, sometimes permanent beneficial effect after long use (1 yr +) this is because the receptor changes alter signals into the nucleus and these change the proteins that regulate the genes. In effect, they restore gene functioning to "pre-trauma" baselines.

Answered 12/10/2013

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