Bp 114/74,5mg amlodipine 2x day.sometimes heart rate is low 50 bpm or so. occasional palpitations most of adult life.over the last 12 months dropped 25 lbs through diet.prior to weight loss bp was 145/95,hr was 70 w/o meds. time to adjust bp meds?

No, that blood pressure is optimal for your age. However, most people have reflex tachycardia (high heart rate) with amlodipine but rarely it may cause bradycardia (low heart rate). If your heart rate is below 50 quite often or you have lightheadedness with changing position, I suggest to have Amlodipine changed to a different dihydropyridine calcium channel blocker such as Felodipine as a trial.

It appears as though you have accomplished the primary objective of losing weight. Now come measures to maintain you weight without regaining. Your blood pressure is now normal and it may be possible for your doctor to gradually reduce the amlodipine dose. Regardless, you have accomplished a great deal. Congratuations.