Can hpv infect blood? for instance, i popped a pimple on my face with hpv contaminated finger and which leads to little bleeding?

There is a small chance of the virus transited to your face. HPV usually is transmitted by direct contact. Any virus can infect blood.

Define "infect". HPV is from a family of viruses where strains focus on certain tissue types where that strain will thrive. It is "planted" in those sites by direct contact and tend to stay localized to that tissue. Common skin wart strains do not cause genital warts. Cancer associated strains do not cause skin warts. It does not act like a flu and go everywhere to infect all tissues.

It depends on what you mean. HPV will not cause sepsis or proliferate in blood. There are many stains of HPV and each has its preferred site to infect. The virus causing genital warts may not cause warts on the face. Get HPV vaccine.