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A member asked:
Can chronic kidey stones (since 2012) cause egfr to fluctuate? hasn't been greater than 90 since 2015, it ranges 70-80. jan egfr was 74 & chloride 101meq/l, march egfr was 71 w/ 3 stones. permanent damage or can it improve?
2 doctors weighed in across 2 answers
Yes, GFR is estimated and can vary greatly based on hydration level at the time the test is done. Kidney stones and damage done in time may contribute as well, establishing with a nephrologist should help.
Answered 9/23/2021
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The kidney damage from kidney stones (nephrolithiasis) is mostly irreversible but slow progression except in acute condition when stone causes ureteral obstruction and acute kidney injury then relieving the obstruction will improve the function. In you case, problem is chronic so low GFR will not be reversible but the change from January to March was likely due to change volume and blood pressure.
Answered 9/25/2021
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