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A 26-year-old male asked:

Why do some people do not respond at all to corticosteroid nasal sprays( fluticasone,mometasone)? do steroids fail to reduce inflammation in such people?does it also mean that steroid would be unable to cause any side effect in such bodies/people?

2 doctor answers3 doctors weighed in
Dr. Sue Ferranti
Internal Medicine 31 years experience
It doesn’t mean that the steroids are not decreasing inflammation. It could mean that there is another etiology for the symptoms. For example, if a nasal polyp is causing the symptoms, the polyp may need to be removed to treat the symptoms. So, if the nasal steroids are not helping, see an ear/nose/throat specialist for evaluation/treatment. Best of luck to you!
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Silviu Pasniciuc
Internal Medicine 29 years experience
Diagnosis has to be questioned in such cases, side effects remain otherwise possible with prolonged steroid use.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Aug 29, 2021

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