U.S. doctors online nowAsk doctors free
TN
A 61-year-old male asked:

What is the recommended way to lisinopril 10mg to control bpand isosorbide mononitrate 30mg for myocardial ischemia.this combination dropped bp systolically to a very low number, make heart to race and pond. what dose adjustments is recommended?

2 doctor answers4 doctors weighed in
Dr. Hiep Le
Dr. Hiep Leanswered
Nephrology and Dialysis 42 years experience
You should take Isosorbide mononitrate in the morning and Lisinopril at dinner time. Isosorbide mononitrate is not a strong BP med so I wonder what you are feeling are the adverse effects of Isosorbide mononitrate rather than the symptoms of low blood pressure. How low is the systolic number? If systolic pressure is still less than 100 with that modification, you can cut Lisinopril tablet in half.
Dr. Ramalingaier Parameswaran
Specializes in Cardiology
I suspect the Isosorbide was responsible for the drop in the blood pressure. Was 30 mgm the starting dose? How often? What is the "very low number" for the blood pressure? I would communicate with your physician and ask for his advice. The effect of Isosorbide may also by exaggerated if you are underhydrated. Good luck.

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Free
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Free
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership
Last updated Jun 28, 2021

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.