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A 61-year-old male asked:

Hi doctors. i take metoprolol er, plavix, 81 mg aspirin, & losartan each daily. does it matter in which order i take them? should i take them all at the same time? should i take them in the morning or at night, with or without food or does it matter?

3 doctor answers6 doctors weighed in
None of these drugs interact with each other. You may take them in the morning or at night , together or separately.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Bennett Machanic
Neurology 54 years experience
Your medication combinations are not unusual, and none of these drugs cause any significant drug-drug interactions or additive side effects. As long as you ingest the recommended dosages daily, how you arrange this is of no impact. Follow your physicians' guidelines.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Ramalingaier Parameswaran
Specializes in undefined
Agree entirely.
Apr 9, 2021
Dr. Hiep Le
Dr. Hiep Leanswered
Nephrology and Dialysis 44 years experience
My advice will be taking Metoprolol in the morning and Losartan in the evening. Although these 2 BP meds are long acting meds but taking them separately will keep your BP stable through 24 hours. Furthermore, it is better to take Metoprolol in the morning because this medication slows down the heart rate and the heart rate may dip too much at night time during sleep.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jun 13, 2022
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