HRT side effects ? : HRT after hysterectomy and bilateral ovarian removal can activate endometriosis implants unaffected by removal of ovarian function, causing severe pelvic pain. Leg pain can be associated with clots, also possible secondary to HRT. See your gyn provider, who may recommend stopping HRT and other potential tests for leg pain, at least for time to reduce endometriosis remainders.
Answered 2/18/2021
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