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A 34-year-old female asked:

Can i take bonine with zofran and 25 mg amitriptyline for a few days to prevent motion sickness?

1 doctor answer1 doctor weighed in
Dr. Yvette Kratzberg
Pediatrics 25 years experience
Medications interact: Amitriptyline should NOT be taken with either Zofran or Bonine because it can cause severe side effects including: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation.
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Last updated Feb 8, 2021

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