A member asked:

Can hormones play a role in acute urticaria. was injected with xolair on the 5th of december but it seems to be returning. i had a partial hysterectomy dec 2018. i have sore breasts certain time a month and the hives. is there something i am missing?

A doctor has provided 1 answer

Urticaria: The causes of acute urticaria often are identified but in many cases the cause is elusive. Some causes are probably internal, however Sore breasts are hormone related but urticaria caused by these same hormones would be speculative.Estrogen stimulates mast cells to produce more histamine so that hives could be worse during the first phase of the menstrual cycle when estrogen levels are highes

Answered 1/2/2020

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