Can call the doctor: Usually a person who, on just one occasion, takes twice the dose for an over-the-counter medication will be fine as the medicine wears off. The acetaminophen portion is 325mg per pill, so 2 pills is no problem. The diphenhydramine portion is 50mg per pill, so twice that would be VERY sedating. That's why a person should talk with his or her primary care doctor to see if a doctor's exam is needed.
Answered 6/13/2021
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