Not necessarily: Hydrochlorothiazide is a thiazide diuretic. Aldactone or spironolactone is a potassium sparing diuretic which intentionally allows your body to hold onto more potassium. This would be the opposite effect of HCTZ on your potassium so you would need some blood work done. Also, the benefits may be different based on your other medical problems compared to HCTZ.
Answered 5/8/2018
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