A member asked:

Can spironolactone hctz (hydrochlorothiazide) cause numbess in soles of feet. i was switched from triamterne hctz (hydrochlorothiazide) 3 weeks ago and numbness seems to be escalating. ?

6 doctors weighed in across 2 answers
Dr. Howard Fox answered

Specializes in Podiatry

Spironolactone HCTZ (hydrochlorothiazide): Is not generally known to cause numbness anywhere, but that's not to say it's impossible. But it can cause an adverse reaction that can lead to numbness. You must discuss this with the doctor who prescribed the spironolactone/hctz.

Answered 9/10/2013

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It could: Parasthesias, or abnormal sensations in the skin can be a side-effect of spironolactone-hctz. Do not just stop this medication- talk to your pharmacist and prescribing doctor first.

Answered 7/29/2019

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