Sharp stabbing pain in knee when any weight put on it, and hurts severely when i twist left or right, what could this be?

Meniscus or ligament: It could be many things and would certainly Require an in person physical exam, getting more information about when and how this pain started, and possibly imaging. Please see your primary care provider who may or may not refer you to an orthopedist. Wrapping your knee with a compression or ace wrap, ice, ibuprofen or naprosyn, and elevation may also be helpful.