A member asked:

Is it safe to split 400 mg enteric-coated sam-e tablets and consume half at a time?

2 doctors weighed in across 2 answers
Dr. Oscar Novick answered

Specializes in Pediatrics

By splitting a enteric-coated tablet you may be losing its effectiveness

Answered Apr 15, 2018

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Dr. James Ferguson answered

Specializes in Pediatrics

The enteric coating is designed to get the active contents of SAMe tablets past the destructive action of stomach acid to a place in the small intestines where they will be absorbed. You could cut them, but may lose most of the active med. If you want to take less, invest in a smaller enteric coated dose.

Answered Apr 17, 2018

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