Are the ingredients microcrystalline cellulose and titanium dioxide safe to ingest without any issues? they are on the ingredients label.

Generally OK but:: MIcrocrystalline cellulose is derived from wood pulp. It's generally recognized as safe. It's likely poorly absorbed. but there are theoretical safety concerns- see https://tinyurl.com/y7z5d9w3 Titanium dioxide is commonly used to give tablets a glossy look. I'm more concerned about it's safety; it appears to be a carcinogen and may harm brains- see https://tinyurl.com/yaeaqsvw See my comment.