A member asked:

How does the pathology of multiple sclerosis compare to that of myasthenia gravis?

3 doctors weighed in across 2 answers

Both autoimmune,: Mg is peripheral, ms central. Myasthenia is a disease of the neuromuscular junction, and causes weakness on progressive exertion, or drooping of eyelids or fluctuating double vision. Ms is a disease of brain and spinal cord, and causes weakness and fatigue of a fairly constant type. Loss of vision, bowel and bladder problems, loss of coordination and balance can be seen.

Answered 4/16/2013

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They are different: Myasthenia gravis and multiple sclerosis are entirely different illnesses. Their symptoms, diagnosis, treatment and pathology are different. In MG, there are antibodies that block the neuromuscular junction. This normally causes weakness and fatigue. In MS, there are lesions of the brain, spinal cord and optic nerves that affect various neurological functions.

Answered 5/20/2016

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