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A 39-year-old male asked:

My wife is 37 and has multiple sclerosis. she wants to get pregnant but i'm afraid that stopping her medication will do her harm. is it safe?

4 doctor answers5 doctors weighed in
Dr. Addagada Rao
General Surgery 56 years experience
Yes: On the contrary ms will reduce the exacerbations , complications rate is same as non ms patients including postpartum issues, how ever need a team of collaborating physicians during pregnancy to carry through , when to take or to stop medications , speak to her doctor. Good luck.
Dr. William Gaya
Neurology 29 years experience
Multiple sclerosis: It is a concern. Removing certain medications can increase the relapse rate immediately after stopping the medication (immune reconstitution syndrome). This is not seen with the older "platform" therapies. Copaxone (glatiramer) is category b for pregnancy. Nevertheless, all my patients have opted to stay off medication during their pregnancies. Good thing is relapse rate is reduced during 2-3rd trimester.
Dr. Liza Kunz
Maternal-Fetal Medicine 21 years experience
Preconception appt: It sounds like your wife should make appointments with her neurologist, and her ob, to discuss the risks, and outline a plan for how they would manage her during pregnancy. Ms patients typically do well if their disease is well controlled prior to pregnancy.
Dr. Bennett Machanic
Neurology 52 years experience
Pregnancy protects: MS stabiilzes in most cases during pregnancy with decreased disease activity until about 6 weeks after labor and delivery. Depending upon your medication, need to stop prior to conception, but no reason why she cannot have a child.

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Last updated Sep 29, 2016

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