How soon after completing my taper off zoloft is it safe to take tramadol without the risk of seratonin syndrome? took 100 mg for 9 months. feel fine

1 week: The half-life of sertraline is ~ 26 hours. After completing a taper, andafter an additional 6 days, you should have negligible amounts in your system. It is good to have an awareness of the possibility of developing serotonin syndrome. But, honestly, it rarely develops to a significant degree. Many people take multiple medications with serotonin type influences and develop no signs of it.

Risk low: Risk Od serotonin syndrome with Zoloft and tramadol combination is extremely low