My younger brother has aso titer positive around 1600, his age 22 years, he is taking homeopathy but no positive response, kindly advise.

Hmmm....: Truly homeopathic "medications" are made by repeated dilutions, so that the ingredient is not really there anymore (just the "essence" of it remains). That means there is no active ingredient left to cause an response. However, that also implies that the homeopathic "medicine" should be pretty harmless, unless some other non-homeopathic ingredient (such as some other chemical) was added.