A member asked:

Started taking fish oil for bipolar/depression. seem to have increased anxiety and fatigue? normal? will it subside?

3 doctors weighed in across 3 answers
Dr. Carla Enriquez answered

Specializes in Pediatrics

Maybe : Although very little literature support exists for this adverse effect, I have observed this side effect in specific families at a very high rate. If you're like those folks, it won't subside. Since using omega-3 for bipolar/depression, it may interfere with other meds taken, but there is minimal data to support benefit in this setting. Best to discontinue, if symptoms go away, try something else.

Answered 12/10/2013

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Dr. Pamela Pappas answered

Specializes in Psychiatry

Interesting question: Research data does support the use of omega-3's in bipolar depression: http://www.Ncbi.Nlm.Nih.Gov/pubmed/21903025 . In these, omega-3's have usually been added to other treatments. Incidence of mania/hypomania was low, but can conceivably happen. Additives or contaminants in some fish oil products could be an issue also. Please work with your own physician on all mood concerns.

Answered 1/27/2014

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Insufficient data: Whether the studies showing this are accurate is very problematic. Strongly suggest that you consult again with the psychiatrist treating your bipolar disorder. There are multiple ways of approaching this and an expert in this area can surely help you. Good luck and hope you improve soon.

Answered 5/13/2013

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