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A member asked:
What is the pathological step in which nsaids cause acute gatritis?
A doctor has provided 1 answer
PG deficiency: The pathophysiology of side effects in the stomach associated with use of NSAIDs is related to COX 1 and 2 inhibition and a resultant prostaglandin (PG) deficiency. In this way, NSAIDs cause damage to the stomach’s mucosal lining, leading to ulcers and increased acidity in the small intestine, which may be treated by drug classes like the proton pump inhibitors PPIs (e.g., omeprazole).
Answered 7/2/2017
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Related Questions
A member asked:
What is the difference in treatment of gastritis with only stomach pain and pain combined with vomiting. does one dose of nsaid cause single or both?
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If stomach ulcer/gastritis is caused by use of nsaid. Can it heal itself without the help of a proton pump inhibitor if nsaid is stopped completely?
A doctor has provided 1 answer
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