I have been feeling itchy on my hands and legs the last few days, this only happens in the evening times. today i checked my knee. a part of it was al?

I suspect that: maybe a key part of your question was cut off..your observation about something on your knee. The most usual cause of itchy hands is eczema or an irritant causing dermatitis/skin inflammation. Simple dry skin is the usual cause of leg itching. Is there a rash? redness? I would try simply moisturizing lotion to your legs, and perhaps a 1% hydrocortisone cream for your hands. If not better, to Derm